The Jackson Laboratory

Monitored Agents List

We monitor for the same agents in all of our JAX® Mice, Clinical & Research Services (JMCRS), Research and Preclinical Services barriers. Exclusion policies and policies related to shipping and notification of customers differ depending on the facility's health status and barrier level as described below.

Organisms excluded from all Jackson Laboratory animal rooms are listed in Table 1.

Table 1. Excluded (ES) Organisms:

If an excluded organism is detected in a room, all shipping is stopped from the affected room and customers are notified of the finding. See below for more details.

Organisms Excluded (ES)1 From All JAX Animal Rooms
VirusesBacteria, Mycoplasma & FungiParasites & Protozoa
Ectromelia virus (agent causing mouse pox)Bordetella spp.Encephalitozoon cuniculi
GDVII (Theiler's mouse encephalomyelitis) virusFilobacterium rodentium (CAR bacillus)Fleas, fur mites, lice
Hantaan virus (hantavirus)Citrobacter rodentium (Citrobacter freundii 4280)Follicle mites
K virusClostridium piliformePinworms
Lactic dehydrogenase elevating virus (LDEV)Corynebacterium kutscheriRoundworms & other helminths
Lymphocytic choriomeningitis (LCMV)Corynebacterium bovis§Tapeworms
Mouse adenovirus (MAV)Mycoplasma pulmonis 
Mouse cytomegalovirus (MCMV)Salmonella spp. 
Mouse hepatitis virus (MHV)Streptobacillus monoliformis 
Mouse minute virus (MMV)  
Mouse parvovirus (MPV)  
Mouse thymic virus (MTV)  
Murine chapparvovirus (MuCPV)  
Pneumonia virus of mice (PVM)  
Polyoma virus  
Reovirus 3 (REO 3)  
Rotavirus (Epizootic diarrhea of infant mice [EDIM])  
Sendai virus  

Table 2 lists the organisms that may be Excluded (ES), Non-tolerated (N) or Tolerated (T) in an animal room, depending upon the room's health status, or in the case of the Research Animal Facility (RAF), upon the barrier level of the room.

ES (Excluded) = If an excluded organism is detected, it must be eliminated from the room. All shipping is stopped from the affected room and customers are notified of the finding as described below.

N (Non-tolerated) = If a non-tolerated organism is detected, efforts will be made to eliminate it from the room, and a notification of the finding will be posted on the JAX website. The finding will be noted on the health report for the room, but shipping from the room will not be stopped.

Click on the Notification of Outbreaks and Shipping Policy link below for a more detailed description.

T (Tolerated) = If a tolerated organism is detected, the finding will be noted on the health report, but no efforts will be made to eliminate it, shipping will not be stopped, and customers will not be notified.

Any concern about agents we monitor but do not stop shipments for, should be communicated to JAX Customer Service in advance or at the time orders are placed.

Table 2. Organisms excluded or tolerated depending upon the Health Status or Barrier Level of the room

 JAX® Mice, Clinical & Research Services (JMCRS) & Preclinical Services Health StatusJAX Research Animal Facility
(RAF) Barrier Level
OrganismPathogen & Opportunistic-FreePathogen-FreeElevated BarrierIntermediate BarrierLow Barrier
Demodex musculiNNNot TestedNot TestedNot Tested
Mouse Norovirus (MNV)ESESNNN
Beta-hemolytic Streptococcus spp. (non-group D)NNNNN
Helicobacter spp.NNNNT
Klebsiella pneumoniaeNTNTT
Klebsiella oxytocaNTNTT
Rodentibacter pneumotropicus/Rodentibacter heyliiNNNNT
Pasteurella multocidaNNNNN
Pneumocystis murina§NNot TestedNNot TestedNot Tested
Pseudomonas aeruginosaNNNNN
Proteus mirabilisNNNTT
Staphylococcus aureusNNNNN
Streptococcus pneumoniaeNNNNN
Nonpathogenic protozoa (e.g. trichomonads)NNNTT
Opportunistic protozoa (e.g. Giardia, Spironucleus)ESESNNT
Yersinia enterocoliticaNNNot TestedNot TestedNot Tested
Yersinia pseudotuberculosisNNNot TestedNot TestedNot Tested
Mycoplasma spp.ESESNot TestedNot TestedNot Tested
Toxoplasma gondiiESESNot TestedNot TestedNot Tested

All the organisms listed in Tables 1 and 2 are listed in The Jackson Laboratory's Animals Health Reports except as noted.

§ Corynebacterium bovis and Pneumocystis murina are only monitored in rooms where severely immunodeficient mice are housed.

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